Our new diffusion chamber is finally here. Take a look at the photos first – in our next group meeting you can see the real thing. Today I will test its usability and reliability. Please keep in mind this is only the prototype, there must be upside space for improvement.
Hi all, Previously we described a two-compartment flow system integrated with a nanoporous membrane in between; and we showed that the nanporous membrane effectively reduces fluid flow from one compartment to the next. Seeing that today is our last NRG meeting this summer, I will present a revisit to the prediction of flow distribution within the membrane-based…
Small DNA oligomers behave like stiff cylindrical rods. They have both rotational and translational diffusion, and this is of interest when considering how such a rod will diffuse through a nanopore. In this post I briefly consider the effects of rotational and translational diffusion of cylinders of different lengths. The rotational diffusion coefficient can be…
Bob and I are trying to determine which wet etch would be appropriate to use to remove the native oxide inside the pores before membrane liftoff. The issue is when removing the native oxide, we will remove part of the membrane. So far, we removed native oxide from bare silicon wafers using 50:1 HF. For…
I took a look back through the Melvern data I collected, particularly focusing on changes in the intensity data in the BSA-DDM solution (the previously posted plots were of number data). When I compared the peak intensities for BSA, DDM, and DDM-BSA complex I noticed that the intensity peaks fall over the same size distribution…
Introduction Endothelial cell detachment under flow on porous substrates has been a concern in our sepsis research since I began my work in the lab, and some time before that as well. As we plan on moving to microfluidic models that incorporate larger pore substrates and physiological shear stresses for extended periods of time, it…
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