NSF STTR Goals
- Phase II submission August 1, 2016 or January 30, 2017
- UR Tasks – Biocompatibility by Feb. 1 2016
- Channel design optimization by November 2015
In order to test the efficacy of any dialysis treatment, we need induce uremia in our animal model. We choose to forgo the surgical approach of performing a 5/6 nephrectomy via ligation for the simpler diet based approach. Feeding the animals a diet containing adenine is meant to raise the level of urea in the…
Now that we have a number of ways to quantify the nanostructure of different npMgF2/npAu film stacks, we can begin an optimization experiment for which combination of factors will be useful to us. To explore the space of outcomes, we have a set of Factors at a certain number of Levels. These produce a set…
Adding pockets (250 micron long, 76 micron deep) to the bottom of the channel (channel is 500 microns wide, 125 deep) in a 4 layer PETL (1 inch long chip) promotes disruption of laminar flow.
Yesterday, Chris, Dave, Graham and I were (exhaustively) trained on the Asylum AFM in Rick Waugh’s lab. We had an overview of the basic features of the AFM and got some real data, as well. The top panel is a height image of the pnc-Si chip with the well side down. Notice the slight decrease…
Following my fabrication process from my previous post, here are the results from my flow test of BBB device v2.6: The difference in the quality of the electrodes is apparent from these images. The microscope slide electrode was difficult to spin coat, resulting in an uneven photoresist coating, and worse patterning. Etching in 12M HCl…
According to recent cell adhesion studies on aminosilanized pncSi, no significant difference between adherence to the silanized and non-silanized surfaces was found. This could have been due to the adsorption of protein from the cell growth media onto the surface nullifying the effect due to silanization which is supposed to make it hydrophobic. ‘If silane…