Tendon-on-Chip Platform for Modeling Inflammation and Fibrosis in Tendon Injury

Since the last post we have been working on obtaining replicates with wafer 101 chips.  The goal was to show salt dependent filtration changes.  These chips were different from the ones originally used in that the pores were much smaller (7-15nm diameter) and did not exhibit any merging.  It was suggested that we perform an…

I’ve been on a Sepcon assembly binge, and I thought I would post my assembly statistics. On 12/15/13 (assembly “L”) I broke 28 chips out of wafer 1070. 3 chips were visually damaged by the break-out process, 1 was already defective. After inserting the chips into the sepcon housing, testing with 5 psi nitrogen revealed…

I guess there was a mistake in the last permeability plot.  The real data for the 4 bar plot should look like this: Unfortunately that doesn’t look so good anymore.  The third bar though is the one that I originally processed to have many more pores (w705).  The reprocessing gets it down in the 8%…

There has been some confusion lately with what we should name the compartments in diffusion.  Here’s what I’ve come up with: Top/Compartment with initial sample: Retentate Bottom/Compartment to which things diffuse: Dialysate The original word we were using for dialysate, filtrate, implies an active process and was criticized by scientists at NAMS.  While dialysate implies…

I repeated the first degradation experiment (posted here) to confirm the results.  I also tracked discoloration of the samples this time.  As before, I used 1X PBS, but this time, the entire assay was performed in the 37C oven. Discoloration pictures: The PSi sample starts with a new rainbow coloration and then completely discolors to…