The future of the Goergen Hall Basement

We now have a linear standard curve for sodium fluorescein (Na-F) in clear 24-well plates.  What is the detection limit? The detection limit is defined as the lowest background-corrected concentration that is 3 standard deviations above the noise of the background.  The background here is HBSS with 10mM HEPES. I measured the dilutions a four…

The Wiesner lab at Cornell (whom you may remember as the discoverer of the neutrally charged but highly fluorescent “C-dots” Jess used for her charged-based separation work) are about to publish Asymmetric Organic-Inorganic Hybrid Membrane Formation via Block Copolymer-Nanoparticle Co-Assembly in Nano letters. Building upon their previous work on block copolymer self-assembling films, they have added titanium dioxide nanoparticles…

Vincent has asked us to integrate our nanoporous filter on top of a thin layer of silicon nitride, so that he can clean up his analyte before being exposed to his single nanopore (fabricated using a dielectric breakdown). There are many different ways to join silicon wafers together. Specifically, we wish to create the following…

Here is the most up to date figure that I’ve made to compare the simulated and experimental separation results.  I went back through the x-ray crystals and remeasured the longest distances in the molecules.  I used the radii to rerun the simulations and plotted them against protein and rhodamine diffusion data.  Here are the results:…