University of Rochester
U2C Center
Translational Center for Barrier Microphysiological Systems - Protocols
TraCe-bMPS accelerates development and adoption of human-relevant barrier models—enabling rigorous, reproducible microphysiological systems for drug discovery, toxicology, and regulatory decision-making.
- Focus
- BBB, NVU, retina, gut, lung & other barriers
- Core strength
- Modular µSiM nanomembrane platform + validation tooling
- Outputs
- Protocols, SOPs, datasets, benchmarking & training
Featured protocols
Assembling µSiM Devices with Flow Insert
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Endothelial Cell Growth and Maintenance in the µSiM with a Flow Insert
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Seeding Cells in Flow Insert - NPN Version
View protocol →About TraCe-bMPS
TraCe-bMPS is a translational hub for barrier-focused microphysiological systems (MPS), supporting fit-for-purpose model development, standardized protocols, benchmarking, and dissemination across academic, industry, and regulatory stakeholders.
- Validated barrier assays with clear acceptance criteria and documentation
- Modular µSiM nanomembrane platform enabling rapid model iteration
- Training materials and SOP frameworks to improve reproducibility